Guide

The one chart I use to run a tissue culture lab

Every week a tissue culture lab has to answer one question before it does anything else: what needs to move? Which cultures are due to be subcultured, which are ready to advance, which are ready to ship. One chart answers all of it at a glance, and it is the chart I open first every single week.

Clear culture vessels of multiplying plantlets on a stainless steel lab bench.
Each vessel holds several plants, and a lot is a group of vessels like these. The chart counts the plants across every lot you hold, sorted by how old they are.

It is not a fancy chart. It is a stacked bar of the plants you currently hold, grouped by the week each lot was made. But because it is placed by age, it quietly tells you your whole work list. This is how it is built, and how to read it.

One bar per week, colored by where it is

Each column is the inventory you hold right now, sorted into the week its lot was created. The height of a column is a plant count. The colors are the growth stage each lot sits in. Because every bar is placed by the week the material was made, the chart is really a picture of age: the leftmost bars are your oldest inventory, and the right edge is what you made this week.

How each bar is counted

Net inventory = plants you made, minus plants you have already used, minus plants merged out of the lot.

Made. The initial count when the lot was created. Used. Everything pulled from that lot into the next stage, plus losses. Merged out. When you combine small lot numbers into one, the emptied lots drop off so nothing is double counted.

The result never shows a plant twice, and never shows a plant you no longer have. What is on the chart is what is physically on your shelves.

The production line

Here is one of the production networks we actually run. Multiplication is the engine: every subculture multiplies the material about 2.5 times. From there it flows one way down the line, into Base, Pre-Rooting, Induction, Rooted Transitioning, and finally Shipping. Each arrow carries a rate. A percentage is the share that survives the step. A multiple, like 1.4 times, is a step where one culture is cut into more pieces. The chart below is built from this network running at a steady pace: 10,000 plants made in Multiplication every week, trickling down the line at each of these rates.

subculture · 2.5× 85% 80% 1.4× 95% 70% to customers Multiplication DKW-X 35 days Base StatX5 35 days Pre-Rooting Char-500 28 days Induction Large Chandler-Indi 4 7 days Rooted Transitioning 128-Cell EP 42 days Shipping Reused 14 days
Each box shows its stage, the medium it runs on, and its residence time in days. A stage that loops, like Multiplication, has a clock: leave a culture past its window and it crowds, browns, and loses vigor. That clock is exactly what the inventory chart makes visible.

Why age is the whole point

Every stage has a residence time, printed on each box in the diagram: the days a culture sits there before it moves to the next stage. Multiplication is 35 days, which is five weeks, so it fills five columns. Rooted Transitioning is 42 days, six columns. Induction is only seven days, a single column. Each color runs one column for every week of its residence, from what entered this week to the oldest week still on the shelf. That oldest week is the one up for work, so within each color the leftmost bar is your list for this week. For Multiplication, that means the cultures to subculture.

Here is that chart, built from 10,000 plants made in Multiplication each week trickling down the line. Shipping is left off: once plants ship they are no longer inventory you hold, so the chart stops at Rooted Transitioning, the last stage still on your shelves. The right edge is this week, and every column to the left is one more week back from today. Switch between growth stage and the medium each stage runs on.

made earlier, act firstmade this week
Sample data for a lab making 10,000 plants a week in Multiplication. Each stage holds several weeks of material at once. The far-right column is the current week; each column left is one week earlier. Hover a bar for its count.

Growth stage is the view you act on. Medium is the view you plan supplies from: it stacks the same plants by the recipe each stage runs on, so you can see how much of each medium you need to make this week.

From a chart to a move list, every week

Reading it is one motion. Within each stage, the bars older than that stage's residence time are ready to move on. The panel under the chart does the arithmetic for every stage at once, and turns the picture into a move list you can hand to a hood tech: how many to subculture, how many to advance, how many to ship.

This is where the inventory chart meets the production network. The network knows the rate of each step, so once you know how much you are subculturing this week, you know roughly how much you will hold at every downstream stage next month, and whether that clears your orders or leaves a gap. The inventory chart is the present. The network turns it into the forecast.

StageResidenceWhat the chart is telling you
Multiplication35 daysthe engine. oldest bars are due to subculture
Base35 daysoldest bars ready to move to pre-rooting
Pre-Rooting28 daysready to move into induction
Induction Large7 daysmoves fast, clears in about a week
Rooted Transitioning42 daysoldest bars are ready to ship
The habit

Open this chart first, every week. Left to right is old to new. Within each color, the oldest bars are work waiting. Almost everything else you do with it is a variation on that one read.

Get new posts by email

I write these now and then. Leave your email and I will send the next one. No spam, and you can unsubscribe any time.

Double opt-in: we send a confirmation email first.

← All library entries